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Book Flights from Panama City to Medellin will help you to find the best deals on flights from Panama City to Medellin. With our search technology, effortlessly searching flight routes across hundreds of airlines has never been easier or more convenient. With, we aim to make it simple and quick to search, select and save on the flights that best suit your needs and budget.

No matter if you are traveling for business or pleasure, we offer a wide range of deals from business class discounts to last minute flight deals to destinations like Medellin. Whether you are planning ahead or looking for last minute tickets, CheapOair has the right flights at the right price. After booking your ticket, explore this page to view blog posts about this destination, learn more about hotels near MDE and read reviews from others who booked their flights with

Frequently Asked Questions - Panama City to Medellin Flights

  • When does the first flight of the day depart from PTY?

    7:23AM Copa Airlines Flight #807

  • When does the last flight depart to MDE?

    9:27PM Copa Airlines Flight #678

  • What is the travel distance between Panama City and Medellin?

    326 miles

  • How many weekly flights are there between PTY to MDE?

    There are 12 weekly flights between PTY and MDE.

  • How many daily flights fly between Panama City and Medellin?

    There are 1 daily flights between PTY and MDE

  • Which is the busiest day in terms of passengers traffic between PTY to MDE?


  • Which is the nearest airport to Medellin, Colombia?

    Enrique Olaya Herrera Airport

  • Which is the nearest airport to Panama City, Panama?

    Paama Airport